Zavesca Cares™

Zavesca Cares support for people taking ZAVESCA.

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Third-Party Organizations that can help

National Gaucher Foundation

This organization is dedicated to promoting education, awareness, and treatment of Gaucher disease.

Learn more
indicate patient brochure

Understanding ZAVESCA® (miglustat) therapy is an important first step.
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indicate simple steps

Simple steps for making the most of ZAVESCA® (miglustat).
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indicate nutrition

Helping yourself with healthy choices.
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indicate zavesca cares

Zavesca Cares™ support for people taking ZAVESCA® (miglustat).
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ZAVESCA® (miglustat) patient support

ZAVESCA patient support is provided by Actelion Pharmaceuticals US, Inc., the company that makes ZAVESCA, and by Accredo, a specialty pharmacy that ensures patients have continued access to their medication.

Helpful resources

Select any of the links below to download information about type 1 Gaucher disease, ZAVESCA therapy, and healthy dietary choices that can help with this condition. Please discuss any comments or questions you may have with your doctor.


Accredo®

ZAVESCA is not available at your local pharmacy. Accredo is a specialty pharmacy that sends ZAVESCA to you on the direction of your doctor and can provide information such as:

  • What to expect from ZAVESCA
  • Making the most of treatment

With Accredo's services, no trips to the pharmacy are necessary to pick up your ZAVESCA prescription or order refills.

Third-party organizations that can help

National Gaucher Foundation
www.gaucherdisease.org
1-800-504-3189

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IMPORTANT SAFETY INFORMATION

What should I tell my doctor before taking ZAVESCA?

Before you take ZAVESCA tell your doctor if you:

  • have kidney problems
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if ZAVESCA will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ZAVESCA passes into your breast milk. You and your doctor should decide if you will breastfeed or take ZAVESCA. You should not do both.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZAVESCA may affect how other medicines work.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I take ZAVESCA?

  • Take ZAVESCA exactly as your doctor has prescribed.
  • Take Zavesca at the same time each day.
  • If you miss a dose of ZAVESCA, skip that dose. Take the next ZAVESCA capsule at the usual time.

What are the possible side effects of ZAVESCA?

ZAVESCA may cause serious side effects including:

  • Numbness, tingling, pain, or burning in your hands or feet (peripheral neuropathy). Call your doctor right away if you get numbness, tingling, pain, or burning in your hands or feet.
  • Your doctor may test your nerves (neurological exam) before you start ZAVESCA and during treatment with ZAVESCA.
  • New or worsening hand tremors (shaky movements). Tremors are common with ZAVESCA and may begin within the first month of starting treatment. Sometimes the tremors may go away between 1 to 3 months with continued treatment. Your doctor may lower your dose or stop ZAVESCA if you develop new or worsening hand tremors. Call your doctor right away if you get new hand tremors while taking ZAVESCA or if the hand tremors you already have get worse.
  • Diarrhea is common with ZAVESCA and sometimes can be serious. Your doctor may prescribe another medicine (anti-diarrheal) to treat diarrhea if it is a problem for you and may recommend changes to your diet, such as avoiding foods high in carbohydrates. Talk with your doctor about your diet if you have diarrhea.
  • Weight loss is common with ZAVESCA and sometimes can be serious. You may lose weight when you start treatment with ZAVESCA.
  • Low platelet count is common with ZAVESCA and can be serious. Your doctor may do blood tests to monitor your blood platelet count.

The most common side effects of ZAVESCA are:

  • Weight loss
  • Stomach pain
  • Gas
  • Nausea and vomiting
  • Headache, including migraine
  • Leg cramps
  • Dizziness
  • Weakness
  • Vision problems
  • Muscle cramps
  • Back pain
  • Constipation
  • Dry mouth
  • Heaviness in arms and legs
  • Memory loss
  • Unsteady walking
  • Loss of appetite
  • Indigestion
  • Numbness, tingling, pain, or burning of your skin
  • Stomach bloating
  • Stomach pain not related to food
  • Menstrual changes

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of ZAVESCA. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information and Patient Information.

cp-113989v2

1.ZAVESCA® (miglustat) full prescribing information. Actelion Pharmaceuticals US, Inc.

What is ZAVESCA?

ZAVESCA is a prescription medicine used alone to treat adults with mild to moderate type 1 Gaucher disease. ZAVESCA is used only in people who cannot be treated with enzyme replacement therapy.

It is not known if ZAVESCA is safe and effective in children under 18 years of age.